New considerations in hematopoietic stem cell transplantation for severe combined immunodeficiency: how did newborn screening change our field, and can we finally brake the glass ceiling for haploidentical transplantation?
Abstract
History of HSCT for SCID
Recent advances in HSCT for SCID
Advances in haploidentical transplantation
CD3 TCRαβ CD19 depletion
Graft depletion of CD45RA naive T cells
Post-transplant cyclophosphamide (PTCy)
Advances and challenges posed by newborn screening
Conclusion
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